Renin

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Renin (bahasa Inggris: renin, angiotensinogenase) adalah Renin, also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys in to the circulation in response to renal hypotension and hyponatremia; sympathetic nerve activation via β1-adrenoceptors also triggers the release. [1][2]

Prekursor renin merupakan sebuah peptida dengan panjang 406 rantai asam amino. Renin sendiri memiliki rantai sepanjang 340 asam amino dengan massa 37 kDa.[3]

Rujukan[sunting | sunting sumber]

  1. ^ Phillips, MI.; Schmidt-Ott, KM. (1999). "The Discovery of Renin 100 Years Ago". News Physiol Sci. 14: 271–274. PMID 11390864. 
  2. ^ Tigerstedt, R.; Bergman, P. (1898). "Niere und Kreislauf". Scandinavian Archives of Physiology. 8: 223–271. 
  3. ^ Imai T, Miyazaki H, Hirose S; et al. (1983). "Cloning and sequence analysis of cDNA for human renin precursor". Proc. Natl. Acad. Sci. U.S.A. 80 (24): 7405–9. doi:10.1073/pnas.80.24.7405. PMC 389959alt=Dapat diakses gratis. PMID 6324167.