KLF17

KLF17
Pengidentifikasi
Alias	KLF17, ZNF393, Zfp393, Kruppel-like factor 17, Kruppel like factor 17, ZLF393
ID eksternal	OMIM: 609602 MGI: 2181068 HomoloGene: 12621 GeneCards: KLF17
Lokasi gen (Manusia)
Kr.	Kromosom 1 (manusia)
Akhir	44,135,140 bp
Ontologi gen
Fungsi molekuler	• DNA binding; • GO:0001948 Ikatan protein plasma; • metal ion binding; • nucleic acid binding; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific;
Komponen seluler	• Inti sel;
Proses biologis	• regulation of transcription, DNA-templated; • transcription, DNA-templated; • regulation of transcription from RNA polymerase II promoter; • negative regulation of transcription from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Ortolog
	128209
	75753
	ENSG00000171872
	ENSMUSG00000048626
	Q5JT82
	Q8CFA7
	NM_173484
	NM_029416
	NP_775755
	NP_083692
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Krueppel-like factor 17 adalah protein yang pada manusia disandi oleh gen KLF17.^[4]^[5] KLF17 merupakan faktor transkripsi yang berperan sebagai penghambat langkah awal dalam metastasis kanker payudara.^[6]

Referensi[sunting | sunting sumber]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171872 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Human KLF17 is a new member of the Sp/KLF family of transcription factors". Genomics. 87 (4): 474–82. Apr 2006. doi:10.1016/j.ygeno.2005.12.011. PMID 16460907.
^ "Entrez Gene: KLF17 Kruppel-like factor 17".
^ Huang, Qihong; Zhang, Lin; Coukos, George; Katsaros, Dionyssios; Showe, Louise C.; Klein-Szanto, Andres J.; Gimotty, Phyllis A.; Li, Anping; Gumireddy, Kiranmai (2009-11). "KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer". Nature Cell Biology (dalam bahasa Inggris). 11 (11): 1297–1304. doi:10.1038/ncb1974. ISSN 1476-4679. PMC 2784164 . PMID 19801974. Pemeliharaan CS1: Format PMC (link)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171872 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16460907-4] "Human KLF17 is a new member of the Sp/KLF family of transcription factors". Genomics. 87 (4): 474–82. Apr 2006. doi:10.1016/j.ygeno.2005.12.011. PMID 16460907.

[entrez-5] "Entrez Gene: KLF17 Kruppel-like factor 17".

[6] Huang, Qihong; Zhang, Lin; Coukos, George; Katsaros, Dionyssios; Showe, Louise C.; Klein-Szanto, Andres J.; Gimotty, Phyllis A.; Li, Anping; Gumireddy, Kiranmai (2009-11). "KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer". Nature Cell Biology (dalam bahasa Inggris). 11 (11): 1297–1304. doi:10.1038/ncb1974. ISSN 1476-4679. PMC 2784164 . PMID 19801974. Pemeliharaan CS1: Format PMC (link)

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KLF17

Referensi[sunting | sunting sumber]

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