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DPYSL2

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DPYSL2
Struktur yang tersedia
PDBPencarian Ortolog: PDBe RCSB
Pengidentifikasi
AliasDPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2, dihydropyrimidinase like 2
ID eksternalOMIM: 602463 MGI: 1349763 HomoloGene: 74392 GeneCards: DPYSL2
Lokasi gen (Manusia)
Kromosom 8 (manusia)
Kr.Kromosom 8 (manusia)[1]
Kromosom 8 (manusia)
Lokasi genom untuk DPYSL2
Lokasi genom untuk DPYSL2
Pita8p21.2Awal26,514,031 bp[1]
Akhir26,658,178 bp[1]
Pola ekspresi RNA
Referensi data ekspresi selengkapnya
Ortolog
SpesiesManusiaTikus
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001386
NM_001197293
NM_001244604

NM_009955
NM_001378767

RefSeq (protein)

NP_001184222
NP_001231533
NP_001377

NP_034085
NP_001365696

Lokasi (UCSC)Chr 8: 26.51 – 26.66 MbChr 14: 67.04 – 67.11 Mb
Pencarian PubMed[3][4]
Wikidata
Lihat/Sunting ManusiaLihat/Sunting Tikus

Protein terkait dihydropyrimidinase 2 adalah enzim yang pada manusia dikodekan oleh gen DPYSL2.[5][6]

Interaksi

[sunting | sunting sumber]

DPYSL2 telah terbukti memiliki interaksi dengan CRMP1,[7] alpha 1[8] dan NUMB.

Referensi

[sunting | sunting sumber]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000092964 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022048 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M (Jan 1997). "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution". Gene. 180 (1–2): 157–63. doi:10.1016/S0378-1119(96)00445-3. PMID 8973361. 
  6. ^ "Entrez Gene: DPYSL2 dihydropyrimidinase-like 2". 
  7. ^ Leung, Thomas; Ng Yvonne; Cheong Albert; Ng Chong Han; Tan Ivan; Hall Christine; Lim Louis (Dec 2002). "p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology". FEBS Lett. Netherlands. 532 (3): 445–9. doi:10.1016/S0014-5793(02)03736-5. ISSN 0014-5793. PMID 12482610. 
  8. ^ Nishimura, Takashi; Fukata Yuko; Kato Katsuhiro; Yamaguchi Tomoya; Matsuura Yoshiharu; Kamiguchi Hiroyuki; Kaibuchi Kozo (Sep 2003). "CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth". Nat. Cell Biol. England. 5 (9): 819–26. doi:10.1038/ncb1039. ISSN 1465-7392. PMID 12942088.