Putresina: Perbedaan antara revisi

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Revisi per 14 Juli 2017 13.46

Putresina
Skeletal formula of putrescine
Ball and stick model of putrescine
Nama
Nama IUPAC (preferensi)
Butane-1,4-diamine
Nama lain
1,4-Diaminobutane
Penanda
Model 3D (JSmol)
3DMet {{{3DMet}}}
Referensi Beilstein 605282
ChEBI
ChEMBL
ChemSpider
DrugBank
Nomor EC
Referensi Gmelin 1715
KEGG
MeSH Putrescine
Nomor RTECS {{{value}}}
Nomor UN 2928
  • InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2 YaY
    Key: KIDHWZJUCRJVML-UHFFFAOYSA-N YaY
  • NCCCCN
Sifat
C4H12N2
Massa molar 88,15 g·mol−1
Penampilan Colourless crystals
Bau strong, piperidine-like
Densitas 0.877 g/mL
Titik lebur 275 °C (527 °F; 548 K)
Titik didih 4.044 °C; 7.311 °F; 4.317 K
Miscible
log P −0.466
Indeks bias (nD) 1.457
Bahaya
Piktogram GHS GHS02: Mudah terbakar GHS05: Korosif GHS06: Beracun
Keterangan bahaya GHS {{{value}}}
H228, H302, H312, H314, H331
P210, P261, P280, P305+351+338, P310
Titik nyala 51 °C (124 °F; 324 K)
Ambang ledakan 0.98–9.08%
Dosis atau konsentrasi letal (LD, LC):
  • 463 mg kg−1 (oral, rat)
  • 1.576 g kg−1 (dermal, rabbit)
Senyawa terkait
Related alkanamines
Senyawa terkait
2-Methyl-2-nitrosopropane
Kecuali dinyatakan lain, data di atas berlaku pada suhu dan tekanan standar (25 °C [77 °F], 100 kPa).
N verifikasi (apa ini YaYN ?)
Referensi

Putresina, atau tetramethylenediamine, adalah suatu senyawa kimia organik NH2(CH2)4NH2 (1,4-diaminobutane or butanediamine) yang berbau busuk[1] yang berhuungan dengan kadaverina; keduanya dihasilkan melalui pemecahan asam amino dalam organisme hidup dan mati dan keduanya merupakan racun dalam dosis besar.[2][3] The two compounds are largely responsible for the foul odor of putrefying flesh, but also contribute to the odor of such processes as bad breath and bacterial vaginosis.[4] They are also found in semen and some microalgae, together with related molecules like spermine and spermidine.

Referensi

  1. ^ Haglund, William (1996). Forensic taphonomy: The Postmortem Fate of Human Remains. CRC Press. hlm. 100. ISBN 0-8493-9434-1. 
  2. ^ Lewis, Robert Alan (1998). Lewis' Dictionary of Toxicology. CRC Press. hlm. 212. ISBN 1-56670-223-2. 
  3. ^ Kamhi, Ellen, Ph.D., RN, HNC (2007). Alternative Medicine Magazine's Definitive Guide to Weight Loss. Celestial Arts. hlm. 14. ISBN 1-58761-259-3. Ornithine is converted by bowel bacteria into a toxic substance called putrescine, which in turn degrades into polyamines, such as spermadine, spermine, and cadaverine (literally meaning "the essence of dead cadavers"). 
  4. ^ Yeoman, CJ;Thomas, SM; Miller, ME; Ulanov, AV; Torralba, M; Lucas, S; Gillis, M; Cregger, M; Gomez, A; Ho, M; Leigh, SR; Stumpf, R; Creedon, DJ; Smith, MA; Weisbaum, JS; Nelson, KE; Wilson, BA; White, BA (2013). "A multi-omic systems-based approach reveals metabolic markers of bacterial vaginosis and insight into the disease". PLOS ONE. 8 (2): e56111. doi:10.1371/journal.pone.0056111. PMC 3566083alt=Dapat diakses gratis. PMID 23405259. 

Pranala luar

Templat:Amino acid metabolism intermediates