IFNA13

Interferon, alpha 13
Struktur tersedia PDB Ortholog search: PDBe, RCSB Daftar kode id PDB 3UX9
Tanda pengenal
Simbol	IFNA13; IFNA1
ID eksternal	OMIM: 147578 MGI: 3641425 HomoloGene: 68536 GeneCards: IFNA13 Gene
Gene Ontology Fungsi molekul • cytokine activity • interferon-alpha/beta receptor binding Komponen sel • extracellular region • extracellular space Proses biologis • blood coagulation • cytokine-mediated signaling pathway • innate immune response • defense response to virus • type I interferon-mediated signaling pathway • regulation of type I interferon-mediated signaling pathway Sumber: Amigo / QuickGO
Orthologs
Spesies	Manusia	Tikus
Entrez	3447	15962
Ensembl	ENSG00000233816	ENSMUSG00000095498
UniProt	P01562	P01572
RefSeq (mRNA)	NM_006900	NM_010502
RefSeq (protein)	NP_008831	NP_034632
Lokasi (UCSC)	Chr 9: 21.37 – 21.37 Mb	Chr 4: 88.85 – 88.85 Mb
PubMed	[1]	[2]

Interferon alpha-1/13, juga dikenal sebagai IFN-alpha-1/13, adalah protein yang pada tubuh manusia disandikan oleh gen IFNA1 dan IFNA13. IFNA13 adalah gen interferon.

Bacaan lanjutan

• Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes". Biochem. J. 329 (2): 295–302. PMC 1219044 . PMID 9425112. Pemeliharaan CS1: Banyak nama: authors list (link)
• Davila S; Froeling FE; Tan A; et al. (2010). "New genetic associations detected in a host response study to hepatitis B vaccine". Genes Immun. 11 (3): 232–8. doi:10.1038/gene.2010.1. PMID 20237496. 
• Weber H, Weissmann C (1983). "Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli". Nucleic Acids Res. 11 (16): 5661–9. doi:10.1093/nar/11.16.5661. PMC 326304 . PMID 6310510. 
• Lamesch P; Li N; Milstein S; et al. (2007). "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes". Genomics. 89 (3): 307–15. doi:10.1016/j.ygeno.2006.11.012. PMID 17207965. 
• Goeddel DV; Leung DW; Dull TJ; et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs". Nature. 290 (5801): 20–6. doi:10.1038/290020a0. PMID 6163083. 
• Myers MP; Andersen JN; Cheng A; et al. (2001). "TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B". J. Biol. Chem. 276 (51): 47771–4. doi:10.1074/jbc.C100583200. PMID 11694501. 
• Hussain M, Ni D, Gill D, Liao MJ (2000). "IFN-alpha1a gene is the major variant in the North American population". J. Interferon Cytokine Res. 20 (9): 763–8. doi:10.1089/10799900050151021. PMID 11032395. Pemeliharaan CS1: Banyak nama: authors list (link)
• Humphray SJ; Oliver K; Hunt AR; et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081 . PMID 15164053. 
• Siezen CL; Bont L; Hodemaekers HM; et al. (2009). "Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes". Pediatr. Infect. Dis. J. 28 (4): 333–5. doi:10.1097/INF.0b013e31818e2aa9. PMID 19258923. 
• Hardy MP; Owczarek CM; Jermiin LS; et al. (2004). "Characterization of the type I interferon locus and identification of novel genes". Genomics. 84 (2): 331–45. doi:10.1016/j.ygeno.2004.03.003. PMID 15233997. 
• Silva LK; Blanton RE; Parrado AR; et al. (2010). "Dengue hemorrhagic fever is associated with polymorphisms in JAK1". Eur. J. Hum. Genet. 18 (11): 1221–7. doi:10.1038/ejhg.2010.98. PMC 2950898 . PMID 20588308. 
• Janssen R; Bont L; Siezen CL; et al. (2007). "Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes". J. Infect. Dis. 196 (6): 826–34. doi:10.1086/520886. PMID 17703412. 
• Shuai K; Horvath CM; Huang LH; et al. (1994). "Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions". Cell. 76 (5): 821–8. doi:10.1016/0092-8674(94)90357-3. PMID 7510216. 
• Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334. 
• Sen GC, Lengyel P (1992). "The interferon system. A bird's eye view of its biochemistry". J. Biol. Chem. 267 (8): 5017–20. PMID 1371992. 
• Strausberg RL; Feingold EA; Grouse LH; et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 . PMID 12477932. 
• Tiefenbrun N; Melamed D; Levy N; et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. 16 (7): 3934–44. PMC 231390 . PMID 8668211. 
• Nagata S, Mantei N, Weissmann C (1980). "The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha". Nature. 287 (5781): 401–8. doi:10.1038/287401a0. PMID 6159536. Pemeliharaan CS1: Banyak nama: authors list (link)
• Todokoro K, Kioussis D, Weissmann C (1984). "Two non-allelic human interferon alpha genes with identical coding regions". EMBO J. 3 (8): 1809–12. PMC 557600 . PMID 6479148. Pemeliharaan CS1: Banyak nama: authors list (link)
• Schuurhof A; Bont L; Siezen CL; et al. (2010). "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls". Pediatr. Pulmonol. 45 (6): 608–13. doi:10.1002/ppul.21229. PMID 20503287.