Ninein: Perbedaan antara revisi
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←Membuat halaman berisi '{{Infobox_gene}} '''Ninein''' adalah protein yang pada manusia dikodekan oleh gen ''NIN''.<ref name="pmid11004522">{{cite journal |vauthors=Hong YR, Chen CH, Chang JH...' |
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'''Ninein''' adalah protein yang pada manusia dikodekan oleh gen ''NIN''.<ref name="pmid11004522">{{cite journal |vauthors=Hong YR, Chen CH, Chang JH, Wang S, Sy WD, Chou CK, Howng SL | title = Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3beta | journal = Biochim Biophys Acta | volume = 1492 | issue = 2–3 | pages = 513–6 |date=Oct 2000 | pmid = 11004522 | pmc = | doi = 10.1016/S0167-4781(00)00127-5}}</ref><ref name="pmid11162463">{{cite journal |vauthors=Hong YR, Chen CH, Chuo MH, Liou SY, Howng SL | title = Genomic organization and molecular characterization of the human ninein gene | journal = Biochem. Biophys. Res. Commun. | volume = 279 | issue = 3 | pages = 989–95 |date=Feb 2001 | pmid = 11162463 | pmc = | doi = 10.1006/bbrc.2000.4050 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NIN ninein (GSK3B interacting protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51199| accessdate = }}</ref> Ninein, bersama-sama dengan ekspersi paralog protein seperti-Ninein adalah salah satu protein yang penting untuk fungsi sentrosomal. Protein ini penting untuk penentuan posisi dan penahan mikrotubulus minus berakhir di sel epitel. Lokalisasi protein ini untuk [[sentrosom]] membutuhkan tiga ''leucine zipper'' dalam domain melingkar-coil pusat. Beberapa varian transkrip alternatif disambung yang mengkode isoform yang berbeda telah dilaporkan.<ref name="entrez" /> |
'''Ninein''' adalah protein yang pada manusia dikodekan oleh gen ''NIN''.<ref name="pmid11004522">{{cite journal |vauthors=Hong YR, Chen CH, Chang JH, Wang S, Sy WD, Chou CK, Howng SL | title = Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3beta | journal = Biochim Biophys Acta | volume = 1492 | issue = 2–3 | pages = 513–6 |date=Oct 2000 | pmid = 11004522 | pmc = | doi = 10.1016/S0167-4781(00)00127-5}}</ref><ref name="pmid11162463">{{cite journal |vauthors=Hong YR, Chen CH, Chuo MH, Liou SY, Howng SL | title = Genomic organization and molecular characterization of the human ninein gene | journal = Biochem. Biophys. Res. Commun. | volume = 279 | issue = 3 | pages = 989–95 |date=Feb 2001 | pmid = 11162463 | pmc = | doi = 10.1006/bbrc.2000.4050 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NIN ninein (GSK3B interacting protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51199| accessdate = }}</ref> Ninein, bersama-sama dengan ekspersi paralog protein seperti-Ninein adalah salah satu protein yang penting untuk fungsi sentrosomal. Protein ini penting untuk penentuan posisi dan penahan mikrotubulus minus berakhir di sel epitel. Lokalisasi protein ini untuk [[sentrosom]] membutuhkan tiga ''leucine zipper'' dalam domain melingkar-coil pusat. Beberapa varian transkrip alternatif disambung yang mengkode isoform yang berbeda telah dilaporkan.<ref name="entrez" /> |
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==Bacaan lebih lanjut== |
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*{{cite journal | author=Nakajima D |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99 |name-list-format=vanc| author2=Okazaki N | author3=Yamakawa H | display-authors=3 | last4=Kikuno | first4=R | last5=Ohara | first5=O | last6=Nagase | first6=T }} |
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*{{cite journal |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }} |
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*{{cite journal | author=Mack GJ |title=Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome |journal=Arthritis Rheum. |volume=41 |issue= 3 |pages= 551–8 |year= 1998 |pmid= 9506584 |doi= 10.1002/1529-0131(199803)41:3<551::AID-ART22>3.0.CO;2-X |name-list-format=vanc| author2=Rees J | author3=Sandblom O | display-authors=3 | last4=Balczon | first4=Ronald | last5=Fritzler | first5=Marvin J. | last6=Rattner | first6=J. B. }} |
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*{{cite journal | author=Nagase T |title=Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=7 |issue= 4 |pages= 273–81 |year= 2001 |pmid= 10997877 |doi= 10.1093/dnares/7.4.271|name-list-format=vanc| author2=Kikuno R | author3=Nakayama M | display-authors=3 | last4=Hirosawa | first4=M | last5=Ohara | first5=O }} |
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*{{cite journal |vauthors=Ou YY, Mack GJ, Zhang M, Rattner JB |title=CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation |journal=J. Cell. Sci. |volume=115 |issue= Pt 9 |pages= 1825–35 |year= 2002 |pmid= 11956314 |doi= }} |
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*{{cite journal |vauthors=Dammermann A, Merdes A |title=Assembly of centrosomal proteins and microtubule organization depends on PCM-1 |journal=J. Cell Biol. |volume=159 |issue= 2 |pages= 255–66 |year= 2002 |pmid= 12403812 |doi= 10.1083/jcb.200204023 | pmc=2173044 }} |
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*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} |
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*{{cite journal | author=Chen CH |title=Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle |journal=Biochem. Biophys. Res. Commun. |volume=308 |issue= 4 |pages= 975–83 |year= 2003 |pmid= 12927815 |doi=10.1016/S0006-291X(03)01510-9 |name-list-format=vanc| author2=Howng SL | author3=Cheng TS | display-authors=3 | last4=Chou | first4=Meng-Hui | last5=Huang | first5=Chi-Ying | last6=Hong | first6=Yi-Ren }} |
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*{{cite journal |vauthors=Fritzler MJ, Zhang M, Stinton LM, Rattner JB |title=Spectrum of centrosome autoantibodies in childhood varicella and post-varicella acute cerebellar ataxia |journal=BMC pediatrics |volume=3|pages= 11 |year= 2004 |pmid= 14503922 |doi= 10.1186/1471-2431-3-11 | pmc=222907 }} |
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*{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }} |
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*{{cite journal | author=Innocenti M |title=Abi1 is essential for the formation and activation of a WAVE2 signalling complex |journal=Nat. Cell Biol. |volume=6 |issue= 4 |pages= 319–27 |year= 2004 |pmid= 15048123 |doi= 10.1038/ncb1105 |name-list-format=vanc| author2=Zucconi A | author3=Disanza A | display-authors=3 | last4=Frittoli | first4=Emanuela | last5=Areces | first5=Liliana B. | last6=Steffen | first6=Anika | last7=Stradal | first7=Theresia E. B. | last8=Fiore | first8=Pier Paolo Di | last9=Carlier | first9=Marie-France }} |
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*{{cite journal | author=Vizmanos JL |title=NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder |journal=Cancer Res. |volume=64 |issue= 8 |pages= 2673–6 |year= 2004 |pmid= 15087377 |doi=10.1158/0008-5472.CAN-04-0144 |name-list-format=vanc| author2=Novo FJ | author3=Román JP | display-authors=3 | last4=Baxter | first4=EJ | last5=Lahortiga | first5=I | last6=Larráyoz | first6=MJ | last7=Odero | first7=MD | last8=Giraldo | first8=P | last9=Calasanz | first9=MJ }} |
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*{{cite journal | author=Howng SL |title=A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors |journal=FEBS Lett. |volume=566 |issue= 1–3 |pages= 162–8 |year= 2004 |pmid= 15147888 |doi= 10.1016/j.febslet.2004.04.024 |name-list-format=vanc| author2=Hsu HC | author3=Cheng TS | display-authors=3 | last4=Lee | first4=Yun-Lin | last5=Chang | first5=Li-Kwan | last6=Lu | first6=Pei-Jung | last7=Hong | first7=Yi-Ren }} |
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*{{cite journal |vauthors=Stillwell EE, Zhou J, Joshi HC |title=Human ninein is a centrosomal autoantigen recognized by CREST patient sera and plays a regulatory role in microtubule nucleation |journal=Cell Cycle |volume=3 |issue= 7 |pages= 923–30 |year= 2006 |pmid= 15190203 |doi= 10.4161/cc.3.7.947}} |
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*{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }} |
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*{{cite journal |vauthors=Delgehyr N, Sillibourne J, Bornens M |title=Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function |journal=J. Cell. Sci. |volume=118 |issue= Pt 8 |pages= 1565–75 |year= 2005 |pmid= 15784680 |doi= 10.1242/jcs.02302 }} |
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*{{cite journal | author=Cheng TS |title=SUMO-1 modification of centrosomal protein hNinein promotes hNinein nuclear localization |journal=Life Sci. |volume=78 |issue= 10 |pages= 1114–20 |year= 2006 |pmid= 16154161 |doi= 10.1016/j.lfs.2005.06.021 |name-list-format=vanc| author2=Chang LK | author3=Howng SL | display-authors=3 | last4=Lu | first4=Pei-Jung | last5=Lee | first5=Chu-I | last6=Hong | first6=Yi-Ren }} |
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==Referensi== |
==Referensi== |
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Revisi per 16 Desember 2016 07.27
Ninein adalah protein yang pada manusia dikodekan oleh gen NIN.[4][5][6] Ninein, bersama-sama dengan ekspersi paralog protein seperti-Ninein adalah salah satu protein yang penting untuk fungsi sentrosomal. Protein ini penting untuk penentuan posisi dan penahan mikrotubulus minus berakhir di sel epitel. Lokalisasi protein ini untuk sentrosom membutuhkan tiga leucine zipper dalam domain melingkar-coil pusat. Beberapa varian transkrip alternatif disambung yang mengkode isoform yang berbeda telah dilaporkan.[6]
Bacaan lebih lanjut
- Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Mack GJ, Rees J, Sandblom O, et al. (1998). "Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome". Arthritis Rheum. 41 (3): 551–8. doi:10.1002/1529-0131(199803)41:3<551::AID-ART22>3.0.CO;2-X. PMID 9506584.
- Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.
- Ou YY, Mack GJ, Zhang M, Rattner JB (2002). "CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation". J. Cell. Sci. 115 (Pt 9): 1825–35. PMID 11956314.
- Dammermann A, Merdes A (2002). "Assembly of centrosomal proteins and microtubule organization depends on PCM-1". J. Cell Biol. 159 (2): 255–66. doi:10.1083/jcb.200204023. PMC 2173044
. PMID 12403812. - Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 . PMID 12477932.
- Chen CH, Howng SL, Cheng TS, et al. (2003). "Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle". Biochem. Biophys. Res. Commun. 308 (4): 975–83. doi:10.1016/S0006-291X(03)01510-9. PMID 12927815.
- Fritzler MJ, Zhang M, Stinton LM, Rattner JB (2004). "Spectrum of centrosome autoantibodies in childhood varicella and post-varicella acute cerebellar ataxia". BMC pediatrics. 3: 11. doi:10.1186/1471-2431-3-11. PMC 222907 . PMID 14503922.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Innocenti M, Zucconi A, Disanza A, et al. (2004). "Abi1 is essential for the formation and activation of a WAVE2 signalling complex". Nat. Cell Biol. 6 (4): 319–27. doi:10.1038/ncb1105. PMID 15048123.
- Vizmanos JL, Novo FJ, Román JP, et al. (2004). "NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder". Cancer Res. 64 (8): 2673–6. doi:10.1158/0008-5472.CAN-04-0144. PMID 15087377.
- Howng SL, Hsu HC, Cheng TS, et al. (2004). "A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors". FEBS Lett. 566 (1–3): 162–8. doi:10.1016/j.febslet.2004.04.024. PMID 15147888.
- Stillwell EE, Zhou J, Joshi HC (2006). "Human ninein is a centrosomal autoantigen recognized by CREST patient sera and plays a regulatory role in microtubule nucleation". Cell Cycle. 3 (7): 923–30. doi:10.4161/cc.3.7.947. PMID 15190203.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
- Delgehyr N, Sillibourne J, Bornens M (2005). "Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function". J. Cell. Sci. 118 (Pt 8): 1565–75. doi:10.1242/jcs.02302. PMID 15784680.
- Cheng TS, Chang LK, Howng SL, et al. (2006). "SUMO-1 modification of centrosomal protein hNinein promotes hNinein nuclear localization". Life Sci. 78 (10): 1114–20. doi:10.1016/j.lfs.2005.06.021. PMID 16154161.
Referensi
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021068 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Hong YR, Chen CH, Chang JH, Wang S, Sy WD, Chou CK, Howng SL (Oct 2000). "Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3beta". Biochim Biophys Acta. 1492 (2–3): 513–6. doi:10.1016/S0167-4781(00)00127-5. PMID 11004522.
- ^ Hong YR, Chen CH, Chuo MH, Liou SY, Howng SL (Feb 2001). "Genomic organization and molecular characterization of the human ninein gene". Biochem. Biophys. Res. Commun. 279 (3): 989–95. doi:10.1006/bbrc.2000.4050. PMID 11162463.
- ^ a b "Entrez Gene: NIN ninein (GSK3B interacting protein)".