Ranitidin: Perbedaan antara revisi
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'''Ranitidin''', suatu obat golongan [[antagonis H2]], adalah obat yang menurunkan produksi asam lambung.<ref name=AHFS2015/> Obat ini umumnya digunakan dalam pengobatan penyakit [[ulkus peptikum]], penyakit [[refluks gastroesofagus]], dan [[sindrom Zollinger-Ellison]].<ref name=AHFS2015/> Terdapat juga bukti tentatif manfaat untuk ''hives''.<ref>{{cite journal|last1=Fedorowicz|first1=Z|last2=van Zuuren|first2=EJ|last3=Hu|first3=N|title=Histamine H2-receptor antagonists for urticaria.|journal=The Cochrane database of systematic reviews|date=14 March 2012|volume=3|pages=CD008596|pmid=22419335|doi=10.1002/14651858.CD008596.pub2}}</ref> Obat dapat diambil melalui mulut, dengan suntikan ke dalam otot, atau ke pembuluh darah.<ref name=AHFS2015/> |
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Ranitidin adalah obat golongan antagonis H2. |
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==Referensi== |
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[[Kategori: Farmakologi]] |
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Revisi per 20 November 2016 08.12
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 458460406 | IUPAC_name = N-(2-[(5-[(dimethylamino)methyl]furan-2-yl)methylthio]ethyl)-N'-methyl-2-nitroethene-1,1-diamine; dimethyl [(5-{[(2-{[1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine | image = Ranitidine Structural Formulae.png | width = 200 | image2 = Ranitidine-A-3D-balls.png
| tradename = Zantac | Drugs.com = monograph | MedlinePlus = a601106 | licence_US = Ranitidine | pregnancy_AU = B1 | pregnancy_US = B | legal_AU = S2 | legal_US_comment = OTC/RX | legal_UK_comment = P/POM | routes_of_administration = Oral, IV
| bioavailability = 39 to 88% | protein_bound = 15% | metabolism = Hepatic | elimination_half-life = 2–3 hours | excretion = 30–70% Renal
| CASNo_Ref = 
| CAS_number_Ref =
| CAS_number = 66357-35-5
| ATC_prefix = A02
| ATC_suffix = BA02
| ATC_supplemental =
A02BA07 (ranitidine bismuth citrate)
| PubChem = 657345
| IUPHAR_ligand = 1234
| DrugBank_Ref =
| DrugBank = DB00863
| ChemSpiderID_Ref =
| ChemSpiderID = 571454
| UNII_Ref =
| UNII = 884KT10YB7
| KEGG_Ref =
| KEGG = D00422
| ChEBI_Ref = 
| ChEBI = 8776
| ChEMBL_Ref =
| ChEMBL = 1790041
| C=13 | H=22 | N=4 | O=3 | S=1
| molecular_weight = 314.4 g/mol
| smiles = [O-][N+](=O)\C=C(\NC)NCCSCc1oc(cc1)CN(C)C
| InChI = 1/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9-
| InChIKey = VMXUWOKSQNHOCA-LCYFTJDEBT
| StdInChI_Ref =
| StdInChI = 1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3
| StdInChIKey_Ref =
| StdInChIKey = VMXUWOKSQNHOCA-UHFFFAOYSA-N
}}
Ranitidin, suatu obat golongan antagonis H2, adalah obat yang menurunkan produksi asam lambung.[1] Obat ini umumnya digunakan dalam pengobatan penyakit ulkus peptikum, penyakit refluks gastroesofagus, dan sindrom Zollinger-Ellison.[1] Terdapat juga bukti tentatif manfaat untuk hives.[2] Obat dapat diambil melalui mulut, dengan suntikan ke dalam otot, atau ke pembuluh darah.[1]
Referensi
- ^ a b c Kesalahan pengutipan: Tag
<ref>tidak sah; tidak ditemukan teks untuk ref bernamaAHFS2015 - ^ Fedorowicz, Z; van Zuuren, EJ; Hu, N (14 March 2012). "Histamine H2-receptor antagonists for urticaria". The Cochrane database of systematic reviews. 3: CD008596. doi:10.1002/14651858.CD008596.pub2. PMID 22419335.