Serotonin: Perbedaan antara revisi

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[[image:5htsynt_2.png|frame|left|403px|The pathway for the synthesis of serotonin from Trp]]<br style="clear: both;" />
[[Berkas:5htsynt_2.png|frame|left|403px|The pathway for the synthesis of serotonin from Trp]]<br style="clear: both;" />


[[Serotonin]] taken orally does not pass into the serotonergic pathways of the [[central nervous system]] because it does not cross the [[blood-brain barrier]]. However, the [[amino acid]] [[tryptophan]] and its metabolite '''[[5-hydroxytryptophan]]''' ('''[[5-HTP]]'''), from which serotonin is synthesized, can and do cross the blood-brain barrier. These agents are available as [[dietary supplement]]s and may be effective serotonergic agents.
[[Serotonin]] taken orally does not pass into the serotonergic pathways of the [[central nervous system]] because it does not cross the [[blood-brain barrier]]. However, the [[amino acid]] [[tryptophan]] and its metabolite '''[[5-hydroxytryptophan]]''' ('''[[5-HTP]]'''), from which serotonin is synthesized, can and do cross the blood-brain barrier. These agents are available as [[dietary supplement]]s and may be effective serotonergic agents.

Revisi per 17 November 2008 04.22

Serotonin
Struktur kimia serotoninStruktur tiga dimensi
Nama kimia5-Hydroxytryptamine or
3-(2-aminoethyl)-1H-indol-5-ol
Rumusan kimiaN2OC10H12
Massa molekul176.2182 g/mol
Massa monoisotop176.0950 g/mol
Komposisi (berat)N: 15.8970%  O: 9.0793%
C: 68.1598%  H: 6.8638%
Nomor CAS50-67-9
SMILESNCCC1=CNC2=C1C=C(O)C=C2
IUPAC InChI ID1/C10H12N2O/c11-4-3-7-6-12-10-2-1-
8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2

Serotonin (5-hydroxytryptamine, atau 5-HT) adalah suatu neurotransmitter monoamino yang disintesiskan dalam neuron-neuron serotonergis dalam sistem saraf pusat (CNS) dan sel-sel enterochromaffin dalam saluran pencernaan.


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