Asam laktat: Perbedaan antara revisi
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{{chembox |
{{chembox |
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| Verifiedfields = changed |
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| Watchedfields = changed |
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| verifiedrevid = 477002503 |
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| Name = Asam laktat |
| Name = Asam laktat |
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| ImageFile = |
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| ImageFileL1 = |
| ImageFileL1 = 7 Milchsäure.svg |
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| ImageSizeL1 = |
| ImageSizeL1 = 110 |
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| ImageNameL1 = Skeletal formula of lactic acid |
| ImageNameL1 = Skeletal formula of <small>L</small>-lactic acid |
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| ImageCaptionL1 = |
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| ImageNameR1 = Ball-and-stick model of lactic acid |
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| ImageSizeR1 = 130 |
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| IUPACName = 2-hydroxypropanoic acid |
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| ImageNameR1 = |
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''Note:'' The S enantiomer is depicted in each of the structural models included above. |
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| ImageCaption2 = <small>rac</small>-Lactic acid |
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| PIN = 2-Hydroxypropanoic acid<ref name=iupac2013>{{cite book | title = Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book) | publisher = [[Royal Society of Chemistry|The Royal Society of Chemistry]] | date = 2014 | location = Cambridge | page = 748 | doi = 10.1039/9781849733069-00648 | isbn = 978-0-85404-182-4}}</ref> |
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| SystematicName = |
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| OtherNames = Lactic acid<ref name=iupac2013 /><br />Milk acid |
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| Section1 = {{Chembox Identifiers |
| Section1 = {{Chembox Identifiers |
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| IUPHAR_ligand = 2932 |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASOther = <br /><small>D</small>/<small>L</small>: [50-21-5] <br /><small>L</small>: [79-33-4]<br /><small>D</small>: [10326-41-7] |
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| CASNo1_Ref = {{cascite|correct|CAS}} |
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| CASNo1 = 79-33-4 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 330546 |
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| CASNo1_Comment = (<small>L</small>) |
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| CASNo2_Ref = {{cascite|correct|CAS}} |
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| CASNo2 = 10326-41-7 |
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| CASNo2_Comment = (<small>D</small>) |
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| UNII_Ref = {{fdacite|changed|FDA}} |
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| UNII = 33X04XA5AT |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| ChEBI = 422 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = JVTAAEKCZFNVCJ-REOHCLBHSA-N |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 96860 |
| ChemSpiderID = 96860 |
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| SMILES = CC(O)C(=O)O |
| SMILES = CC(O)C(=O)O |
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| C=3 | H=6 | O=3 |
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| MeltingPt =53°C |
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| BoilingPtC = 122 |
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| BoilingPt_notes = @ 15 mmHg |
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| pKa = 3.86,<ref>{{cite book| vauthors = Dawson RM |displayauthors=etal|title=Data for Biochemical Research|location=Oxford|publisher=Clarendon Press|date=1959}}</ref> 15.1<ref>{{cite journal | vauthors = Silva AM, Kong X, Hider RC | title = Determination of the pKa value of the hydroxyl group in the alpha-hydroxycarboxylates citrate, malate and lactate by 13C NMR: implications for metal coordination in biological systems | journal = Biometals | volume = 22 | issue = 5 | pages = 771–8 | date = October 2009 | pmid = 19288211 | doi = 10.1007/s10534-009-9224-5 }}</ref> |
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}} |
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| Section3 = |
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| Section4 = {{Chembox Thermochemistry| DeltaHc = 1361.9 kJ/mol, 325.5 kcal/mol, 15.1 kJ/g, 3.61 kcal/g}} |
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| Section8 = {{Chembox Related |
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| OtherAnions = lactate |
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| OtherFunction_label = [[carboxylic acid]]s |
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| OtherFunction = [[acetic acid]]<br />[[glycolic acid]]<br />[[propionic acid]]<br />[[3-hydroxypropanoic acid]]<br />[[malonic acid]]<br />[[butyric acid]]<br />[[hydroxybutyric acid]] |
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| OtherCompounds = [[1-propanol]]<br />[[2-propanol]]<br />[[propionaldehyde]]<br />[[acrolein]]<br />[[sodium lactate]] |
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}} |
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| Section5 = |
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| Section6 = {{Chembox Pharmacology |
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| ATCCode_prefix = G01 |
| ATCCode_prefix = G01 |
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| ATCCode_suffix = AD01 |
| ATCCode_suffix = AD01 |
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| ATC_Supplemental = {{ATCvet|P53|AG02}} |
| ATC_Supplemental = {{ATCvet|P53|AG02}} |
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}} |
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| Section7 = {{Chembox Hazards |
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| GHSPictograms = {{GHSp|GHS05}}<ref name="sigma">{{Sigma-Aldrich|sial|id=69785|name=DL-Lactic acid|access-date=20 July 2013}}</ref> |
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| HPhrases = {{H-phrases|315|318}}<ref name="sigma" /> |
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| PPhrases = {{P-phrases|280|305+351+338}}<ref name="sigma" /> |
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}} |
}} |
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| |
| Section8 = {{Chembox Related |
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| Formula = C<sub>3</sub>H<sub>6</sub>O<sub>3</sub> |
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| MolarMass = 90.08 g/mol |
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| MeltingPt =<small>L</small>: 53 °C<br /><small>D</small>: 53 °C<br /><small>D</small>/<small>L</small>: 16.8 °C |
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| BoilingPt = 122 °C @ 12 mmHg |
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| pKa = 3.86 at 25 °C |
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| OtherAnions = laktat |
| OtherAnions = laktat |
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| Function = [[asam karboksilat]] |
| Function = [[asam karboksilat]] |
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Asam ini memiliki simetri cermin ([[kiralitas]]), dengan dua [[isomer]]: asam <small>L</small>-(+)-laktat atau asam (''S'')-laktat dan, cerminannya, iasam <small>D</small>-(-)-laktat atau asam (''R'')-laktat. Hanya isomer yang pertama (S) aktif secara [[biologi]]. |
Asam ini memiliki simetri cermin ([[kiralitas]]), dengan dua [[isomer]]: asam <small>L</small>-(+)-laktat atau asam (''S'')-laktat dan, cerminannya, iasam <small>D</small>-(-)-laktat atau asam (''R'')-laktat. Hanya isomer yang pertama (S) aktif secara [[biologi]]. |
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== Pranala luar == |
== Pranala luar == |
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* [http://www.smithsonianmag.com/science-nature/10022381.html Corn Plastic to the Rescue] |
* [http://www.smithsonianmag.com/science-nature/10022381.html Corn Plastic to the Rescue] |
Revisi per 12 Desember 2018 01.46
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Nama | |||
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Nama IUPAC (preferensi)
2-Hydroxypropanoic acid[1] | |||
Nama lain
Lactic acid[1]
Milk acid | |||
Penanda | |||
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Model 3D (JSmol)
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3DMet | {{{3DMet}}} | ||
ChEBI | |||
ChEMBL | |||
ChemSpider | |||
Nomor EC | |||
Nomor RTECS | {{{value}}} | ||
UNII | |||
CompTox Dashboard (EPA)
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Sifat | |||
C3H6O3 | |||
Massa molar | 90,08 g·mol−1 | ||
Titik lebur | 53°C | ||
Titik didih | 122 °C (252 °F; 395 K) @ 15 mmHg | ||
Keasaman (pKa) | 3.86,[2] 15.1[3] | ||
Termokimia | |||
Entalpi pembakaran standar ΔcH |
1361.9 kJ/mol, 325.5 kcal/mol, 15.1 kJ/g, 3.61 kcal/g | ||
Farmakologi | |||
Kode ATC | G01 QP53AG02 | ||
Bahaya | |||
Piktogram GHS | [4] | ||
H315, H318[4] | |||
P280, P305+351+338[4] | |||
Senyawa terkait | |||
Anion lain
|
laktat | ||
Kecuali dinyatakan lain, data di atas berlaku pada suhu dan tekanan standar (25 °C [77 °F], 100 kPa). | |||
verifikasi (apa ini ?) | |||
Referensi | |||
Asam laktat (Nama IUPAC: asam 2-hidroksipropanoat (CH3-CHOH-COOH), dikenal juga sebagai asam susu) adalah senyawa kimia penting dalam beberapa proses biokimia. Seorang ahli kimia Swedia, Carl Wilhelm Scheele, pertama kali mengisolasinya pada tahun 1780. Secara struktur, ia adalah asam karboksilat dengan satu gugus hidroksil yang menempel pada gugus karboksil. Dalam air, ia terlarut lemah dan melepas proton (H+), membentuk ion laktat. Asam ini juga larut dalam alkohol dan bersifat menyerap air (higroskopik).
Asam ini memiliki simetri cermin (kiralitas), dengan dua isomer: asam L-(+)-laktat atau asam (S)-laktat dan, cerminannya, iasam D-(-)-laktat atau asam (R)-laktat. Hanya isomer yang pertama (S) aktif secara biologi.
Pranala luar
- Corn Plastic to the Rescue
- Lactic Acid: Information and Resources
- Lactic Acid Is Not Muscles' Foe, It's Fuel
- Fitzgerald M (January 26, 2010). "The Lactic Acid Myths". Competitor Running.
- ^ a b Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. hlm. 748. doi:10.1039/9781849733069-00648. ISBN 978-0-85404-182-4.
- ^ Dawson RM, et al. (1959). Data for Biochemical Research. Oxford: Clarendon Press.
- ^ Silva AM, Kong X, Hider RC (October 2009). "Determination of the pKa value of the hydroxyl group in the alpha-hydroxycarboxylates citrate, malate and lactate by 13C NMR: implications for metal coordination in biological systems". Biometals. 22 (5): 771–8. doi:10.1007/s10534-009-9224-5. PMID 19288211.
- ^ a b c Sigma-Aldrich Co., DL-Lactic acid.