"I know the human being and fish can coexist peacefully."—Saginaw, Michigan; 29 September 2000
"There's an old saying in Tennessee—I know it's in Texas, probably in Tennessee—that says, 'Fool me once, shame on...shame on you. Fool me -- you can't get fooled again.'"—Nashville, Tennessee; 17 September 2002
"Too many good docs are getting out of the business. Too many OB-GYNs aren't able to practice their love with women all across this country."—Poplar Bluff, Missouri; 6 September 2004
"For every fatal shooting, there were roughly three non-fatal shootings. And, folks, this is unacceptable in America. It's just unacceptable. And we're going to do something about it."—Philadelphia, Pennsylvania, 14 Mei 2001 
"One of the things I’ve used on the Google is to pull up maps."—Wawancara dengan Maria Bartiromo dari CNBC, 24 Oktober 2006.
"Mr. Prime Minister, thank you for your introduction. Thank you for being such a fine host for the OPEC summit."—Berbicara kepada Perdana Menteri Australia John Howard di APEC Summit, 7 September 2007. (Baik AS maupun Australia bukan anggota OPEC.)
"Yesterday, you made note of my—the lack of my talent when it came to dancing. But nevertheless, I want you to know I danced with joy. And no question Liberia has gone through very difficult times."—Berbicara kepada presiden Liberia, Washington, D.C., 22 Oktober 2008 
"Do you have blacks, too?"—Berbicara kepada Presiden Brasil Fernando Cardoso, Washington, D.C., 8 November 2001 
"Vice President mentioned Nigeria is a fledgling democracy. We have to work with Nigeria. That's an important continent."—George W. Bush pada debat presiden di Winston-Salem, North Carolina, 11 Oktober 2000.
"I'm telling you there's an enemy that would like to attack America, Americans, again. There just is. That's the reality of the world. And I wish him all the very best."—Washington, D.C., 12 Januari 2009
"Our enemies are innovative and resourceful, and so are we. They never stop thinking about new ways to harm our country and our people, and neither do we."—Washington, D.C., 5 Agustus 2004
"There's no question about it. Wall Street got drunk—that's one of the reasons I asked you to turn off the TV cameras—it got drunk and now it's got a hangover. The question is how long will it sober up and not try to do all these fancy financial instruments."—Pidato di suatu acara penggalangan dana swasta yang diam-diam direkam oleh seorang reporter, lalu dibocorkan ke berbagai kantor berita, Houston, Texas, 18 Juli 2008